NFL Most Rushing Yards Odds 2024: It’s Down to Barkley and Henry

• Saquon Barkley is the current leader in odds to finish the season with the most rushing yards at -2500

• Derrick Henry (+800) is second

• Both Henry and Barkley ran for 150-plus yards in Week 16

Leading the NFL in rushing is a massive testament to a single player's success, but it also comes down to opportunity. If a player does well enough in the run, they could even be considered an MVP candidate.

Heading into Week 17, there are just two players left in the odds to lead the league in rushing: Philadelphia Eagles running back Saquon Barkley (-2500) and Baltimore Ravens running back Derrick Henry (+800). 

Below, I’ll look at the top two favorites to lead the league in rushing and pick my favorite to lead the league in this category.

NFL 2024 Most Rushing Yards Odds

Odds from Caesars Sportsbook. Click on the odds in the table below to place your bets at Caesars: Bet $1, Double Your Winnings Your Next 10 Bets

Favorites to Lead the 2024 NFL Season in Rushing

Below, I’ll examine Barkley and Henry only as they’re the only players left on the board.

Saquon Barkley - Running Back, Philadelphia Eagles (-2500) at Caesars

Coming off a 65-yard game in Week 15, Barkley responded with 29 carries for 150 yards and two scores in Week 16’s loss to the Washington Commanders. Quarterback Jalen Hurts left the game early, allowing Barkley to get even more carries. 

Those 29 carries were the most he’s had all season.

He’s at 1,838 rushing yards and is 268 away from breaking the single-season record held by Eric Dickerson. 

He finishes out the year against the Dallas Cowboys and New York Giants. These two teams allow 135.9 rushing yards per game or more. The Giants are second-worst, allowing 142.6. 

Barkley should be in for two massive games regardless of whether Hurts plays or Kenny Pickett draws the start in his place.

Use code WSNDYW and Double Your Winnings at Caesars

Derrick Henry - Running Back, Baltimore Ravens (+800) at Caesars

Henry is 202 yards behind Barkley with two games to go, so it’s not looking likely that he’ll catch up. At this point, it would take a Barkley injury or the Giants, and Cowboys run defenses playing otherworldly to round out the season. 

He had a great Week 16, rushing 24 times for 162 yards. This was his best game since Week 7 when he ran for 169 yards against the Tampa Bay Buccaneers. 

Since that game, he’s had 100-plus rushing yards just three times, including the Week 16 performance. 

He’s had less than 20 carries nine times this season. It appears the Ravens have been somewhat saving him for a playoff push, which is great for their Super Bowl aspirations, but as for leading the league in rushing, it will be difficult to pull off. 

He plays the Houston Texans and Cleveland Browns to end the season. Those teams allow 106.8 rushing yards (11th) and 127.4 rushing yards (19th) per game.

Bet $1 at Caesars and Double Your Winnings

Underdog to Lead the 2024 NFL Season in Rushing

As mentioned, Barkley and Henry are the only players listed on the odds to lead the league in rushing. Thus, there are no underdogs to preview.

Join Caesars and Double Your Winnings for the Next 10 Wagers

Who Will Lead the 2024 NFL Season in Rushing

My Pick - Saquon Barkley (-2500) at Caesars

In the final two games of the season, he’s playing two of the six worst rushing defenses and holds a 202-yard lead over Henry. He also has 36 more carries than him. They each have the same yards per carry, so this has really been a matter of who’s gotten more work throughout this season, and it’s been Barkley.

Barkley has two great matchups against divisional opponents. In contrast, Henry has one divisional matchup against a poor run defense but also a game against the playoff-bound Texans, whose run defense is just outside the top 10. 

Barkley will win this, barring something bad from happening to him health-wise.

Use code WSNDYW and Double Your Winnings at Caesars

Who Led the League in Rushing in 2023?

McCaffey led the league in rushing in 2023 with 1,459 yards across 16 games and 272 carries. He averaged 5.4 yards per carry and 14 touchdowns. He added 268 yards on 59 carries in the postseason across three games.

Single-Season Rushing Yard Leader History

According to Pro Football Reference, the single-season rushing yard leaders have been tracked every year since 1932. However, the modern “Super Bowl” era began in 1967. 

Below, we’ll look back at each single-season rushing leader from 1967 and beyond. 

How to Choose the Best Sportsbook for Betting on NFL Most Rushing Yards Odds

Before you start wagering on the NFL single-season rushing leader, you must find the best sportsbook. This is something that many bettors often overlook. If your state has multiple online sportsbooks, you should explore these odds to compare and contrast. 

Here’s some information on some of the most well-known online NFL betting sites. 

*Bonus Bets Expire in 7 Days. One New Customer Offer Only. Add’l terms.

How to Read NFL Most Rushing Yards Odds

Looking at the odds above, you’ll find that every player has a “+” next to their name. During the preseason, there’s a lot of speculation as to who everyone thinks will win, but once the season starts and stats start to accumulate, you’ll begin seeing “-” as players break away from the pact. 

Using examples including $100, here’s how to read “+” and “-” odds. 

• With “+” odds, you’ll win the amount attached on a $100 wager. For example, McCaffrey is +650. If you wager $100 on this and win, you’ll win $650. 

• With “-” odds, you must wager that amount to win $100. For example, if McCaffrey was -650, you’d need to wager $650 to win $100.