Dolphins vs. 49ers Picks, Predictions & Player Props: Two Teams Barely Still Alive

• The 49ers have allowed multiple touchdown passes in three of their last four games

• Dolphins running back De’Von Achane has caught 21 passes over his last three games

• 49ers wide receiver Ricky Pearsall saw four targets in Week 15. This was the most he’s seen since Week 10

The 6-8 Miami Dolphins will host the 6-8 San Francisco 49ers in Week 16 of the NFL season. The Dolphins are in second place in the AFC East, while the 49ers are last in the NFC West. Both teams are 5-9 against the spread this season. 

Below are the odds for this game, my best bet, predictions, and best player props.

Dolphins vs. 49ers Odds

Look below for the moneyline, point spread, and total odds courtesy of Caesars Sportsbook. Using our exclusive link and promo code WSNDYW, you’ll get your next 10 bets doubled in winnings after betting $1.

Dolphins vs. 49ers: My Pick

• My Pick: Dolphins to cover the spread at -1 (-110) at Caesars

This is a bit of an odd game. The spread indicates it’s essentially a pick ‘em between two teams on the fringe of being eliminated. Neither can make the playoffs unless other factors come into play, such as other teams losing. 

At home, though, I’ll side with the Dolphins. Quarterback Tua Tagovailoa has played well enough at home this season, and injuries have decimated the 49ers roster. 

The running game has run for 63 yards or less in two of the last four games. 

I don’t feel overly confident, but I’ll take the home team.

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Dolphins vs. 49ers Predictions

The key difference between these two teams heading into this game is the strength of the recent passing games. 

Over the last three games, the Dolphins have averaged 279.7 yards, while the 49ers have averaged 178.3 per game.

That said, the 49ers have held teams to just 135.3 yards over that span. Two of those games, on a short week, included the Chicago Bears and the Los Angeles Rams. 

Still, the 49ers have allowed multiple passing touchdowns in three of the last four games. 

I’m waiting for more information regarding wide receiver Jaylen Waddle’s status after suffering a knee injury that reportedly won’t require surgery. 

Still, Tagovailoa has thrown for 331 yards or more in two of the last three games. While he had a bad outing last week against a stuff Houston Texans defense, I don’t expect the game kind of defensive prowess from a depleted 49ers squad. 

The 49ers have scored 10 points or less in three of the last four games. 

Admittedly, there might be some meandering in this analysis, but this is one of those games that’s hard to pick due to where these teams are at in the playoff hunt, injuries, and more. 

To summarize: Yes, Tagovailoa had a bad Week 15 game, but he’s been playing better recently than 49ers quarterback Brock Purdy, who has 561 yards, two touchdowns, and one pick over his last three games. 

Take the home team, but do so with caution.

Dolphins vs. 49ers Best Player Props

De’Von Achane Over 5.5 Receptions (+116) at Caesars Sportsbook

Heading into this game, Achane is getting a bunch of action in the passing game. Over the last three games, he’s recorded 21 receptions with no less than six in any game. 

The 49ers are allowing 4.43 receptions per game to the running back position and have allowed six or more in four this season. 

There are some question marks regarding whether Dolphins wide receiver Jaylen Waddle will suit up. If he’s unable to go, this presents even more opportunities for Achane. 

Getting plus line value, I’d take a chance on this one.

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Tua Tagovailoa Over 1.5 Passing TDs (-121) at Caesars Sportsbook

Tagovailoa is coming off a poor outing in Week 15 against the Texans, in which he had just 196 passing yards, one touchdown, and three picks. 

Before that, though, he had two passing touchdowns or more in four straight games. 

The 49ers defense has allowed two passing touchdowns in three of the last four games and an average of 1.21 passing touchdowns per game. 

Those games where they allowed two passing touchdowns came despite each quarterback throwing for 163 yards or less. 

Tagovailoa throws a bunch, and he’ll continue to do so here.

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Ricky Pearsall Anytime TD (+490) at Caesars Sportsbook

I'm digging deep for the last prop, and this could be a quarter or half-unit wager. 

Pearsall has dealt with a lot this season after getting shot before the season. 

Upon returning, though, he saw a decent amount of action, seeing 15 targets in his first three games. 

From there, the usage began to drop, and there was a stretch where he saw just three targets over three games. Two of these included the game on the road against the Bills, in which Purdy had less than 100 passing yards, and the game against the Packers, in which Purdy didn’t play. 

His usage slightly increased last week to four targets, his most since Week 10.

Lining up in the slot, Pearsall will oppose Kader Kohou. 

Kohou has allowed more than 68% of targets thrown his way to be caught and has given up two touchdowns this season, including one two weeks ago.

Of the 49ers wide receivers, Pearsall has the best matchup, and at +490, it’s worth a shot.

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Dolphins vs. 49ers: How to Watch

• When: Sunday, Dec. 22 at 4:25 PM ET

• Where: Hard Rock Stadium in Miami Gardens, FL

• Where to Watch: CBS

Dolphins vs. 49ers Best Promos and Sportsbooks

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Dolphins vs. 49ers Injuries

Dolphins Injuries

• Dolphins wide receiver Grant Dubose has been placed on injured reserve

• Dolphins offensive tackle Kendall Lamm is questionable

• Dolphins wide receiver Dee Eskridge is questionable

• Dolphins offensive tackle Terron Armstead is questionable

• Dolphins wide receiver Jaylen Waddle is questionable with a knee injury

• Dolphins linebacker Bradley Chubb is questionable

49ers Injuries

• 49ers offensive tackle Trent Williams is questionable

• 49ers safety Malik Mustapha is questionable

• 49ers defensive tackle Khalil Davis is questionable

• 49ers safety Ji’Ayir Brown is questionable

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