Best Joe Mixon Prop Bets: Expect Mixon to Stay Hot Against the Colts

• Joe Mixon is coming off a 115-yard game on the ground

• Houston comes in at 5-2 in first place in the AFC South

• Indianapolis is 4-3 in second place in this division

Joe Mixon was one of the NFL Offensive Player of the Year favorites after Week 1, but his output has been inconsistent.

The Texans are coming off a loss over the Packers thanks to a walk-off field goal by Brandon Mcmanus. Despite the loss, Mixon was fantastic throughout the entire contest. 

Indianapolis is currently 18th in the Cold Hard Football Facts Quality Stats Power Rankings, and they have a tough matchup on Sunday. 

In the first game between these teams, Mixon had 30 carries for 159 yards to go with a touchdown. 

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Joe Mixon Over 76.5 Rushing Yards (-115) at bet365

In the last two games, Mixon has rushed for a combined 217 yards and has scored three touchdowns over this span. In the first matchup against the Colts, he ran for 159 yards on 30 carries in a 29-27 win. 

Houston’s offensive line has exceeded expectations this season as Mixon has been on fire in 2024. We like his rushing prop in this matchup because of the volume he has been getting this season. 

Indianapolis has a lot to prepare for in this critical AFC South matchup. Mixon has the fifth most rushing yards in the NFL since 2018 at 6,187. His ability to make defenders miss is terrific and we expect to see that against the Colts.

Look for Mixon to get plenty of carries in this AFC South divisional game, and for him to go over his rushing yard prop. 

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Joe Mixon Over 18.5 Receiving Yards (+100) at bet365

Not only does Mixon do an exceptional job on the ground, but he also has the ability to catch the football out of the backfield. Mixon has been targeted 14 times through the air in his four games this season, and we expect his receiving yards to increase this week. 

He has 83 total yards receiving in 2024, and his ability to make defenders miss after the catch is exceptional. C.J. Stroud is not afraid to check the ball down to him and rely on his running back to pick up yards through the air. 

With star receiver Nico Collins on Injured Reserve, look for Mixon to contribute to the passing game and go over his receiving yards prop this week. 

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Joe Mixon Anytime Touchdown (-150) at bet365

The last prop we are taking with Mixon is an anytime touchdown wager. The odds are very short at -150, but they’re worth taking in this spot as the Texans should have success against the Colts. 

Mixon has five total touchdowns and has scored in all but one of his four starts. Anytime there is a running back utilized a ton on the ground and through the air, touchdown betting is a viable option. 

The Texans will give Mixon every opportunity to score down in the red zone, and we think he will capitalize. Mixon is averaging more than a touchdown per game and we think he keeps this streak alive on Sunday. 

The Indianapolis Colts defense has been relatively shaky this season. The team is allowing 21.3 points per game.

They have been successful on the defensive side of the ball the past two weeks, but they have faced the Titans and Dolphins. They surrendered 37 points to the Jaguars three weeks ago, and the Texans have the same ability to score points. 

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Joe Mixon 2024 Stats

• Carries: 77

• Rushing Yards: 401

• Rushing Touchdowns: 4

• Receiving Yards: 83