AFC South Odds, Predictions, Best Picks 2024: Return of the Mac

• CJ Stroud is completing just 47% of his passes over the last two games

• The Colts will start Anthony Richardson at quarterback after sitting two weeks

• The Jags have lost three straight games by fewer than six points

It seems nobody wants to win the AFC South after ten weeks. The Texans and Colts have lost three of their last four, while the Titans and Jaguars have just two wins. While it may not be exciting to watch, the division struggling presents great odds when betting on the winner.

Below, we will share how we view all four AFC South teams and our pick to win. We’ll be using odds taken from Caesars Sportsbook, which currently offers new bettors a $1,000 First Bet Offer or $250 in Bonus Bets when they sign up using promo code WSN1000. 

Take a look at our podcast, Ride the Line, and explore Grant and Tanner's predictions for AFC South. Also, check out our rankings of the best football betting sites.

AFC South Odds

Odds from Caesars Sportsbook. Click the odds in the table below and claim: $1,000 First Bet on Caesars OR $250 in Bonus Bets.

AFC South Predictions and Favorites to Win

Houston Texans (-20000) at Caesars Sportsbook

The Texans are head and shoulders above the rest of the division on paper, but they haven’t looked like it lately. The team has lost two straight games and three of their last four, all of which were winnable. 

Several issues plagued the Texans over the last two weeks, but the primary problem was CJ Stroud. The talented young passer was bad in the previous two weeks, completing 47% of his passes for 423 yards and throwing two interceptions, taking 12 sacks in the process. We aren’t worried about the 23-year-old, but his struggles may indicate a bigger problem with the offense.

Week 10’s against the Lions may be the worst of their last three losses. The defense picked off Jared Goff five times, but Houston lost the game 26-23 thanks to the poor play of their offense. This team is better than the last few games have shown, but it is clear they are not the juggernaut we expected.

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Indianapolis Colts (+1600) at Caesars Sportsbook

A quarterback switch was not the answer for this Colts team. Two weeks ago, they switched to Joe Flacco, but the team lost both of its next two games. The veteran took seven sacks and four interceptions over those two games, leading the team to turn to Anthony Richardson again.

The Colts’ first pick of the 2023 draft took his benching well, telling reporters it “opened his eyes.” His return again makes Indy an intriguing bet to win the division, sitting just two games behind a struggling Texans team. They have looked like a true playoff team at times this season, and hope Richardson can help them find some consistency. 

The Colts’ remaining schedule isn’t too challenging, which could give Indy the opportunity to capture a surprising division title.

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Tennessee Titans (+6500) at Caesars Sportsbook

After eeking out a win against the Patriots in Week 9, the Titans returned to their losing ways in Week 10. The team actually played a solid game but fell victim to a Chargers team that doesn’t make many mistakes. That doesn’t change that Tennessee is now 2-7, ending any longshot hopes.

There were two silver linings from the Titans’ loss last week. The first was the play of Will Levis, who completed 78% of his passes for two touchdowns without turning the ball over. It appears the young passer is holding onto the ball too long, though that may be better than the back-breaking interceptions he was throwing when under pressure.

The other sliver lining was 23-year-old Tyjae Spears, who averaged 6.7 YPC. It was his second week averaging 4.5 YPC or more, signaling that he may be finding his stride. While he and Tony Pollard could form one of the best backfields in football, it won’t matter much as the Titans consistently play from behind.

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Jacksonville Jaguars (+8500) at Caesars Sportsbook

The Jags’ season is now over after three consecutive heartbreaking losses. Jacksonville all three by five or fewer points, dropping their record to 2-8. Things won’t get any better with Trevor Lawrence out with a shoulder injury. With the season already lost, the team could shut the quarterback down in preparation for next season.

Mac Jones started Week 10 in place of Lawrence and was a disaster. The former Patriot went 14-22 for 111 yards and two interceptions. His struggles limited rookie receiver Brian Thomas Jr’s production, who has become the offense’s most dangerous weapon.

Jacksonville has some franchise-level talent to rebuild around, but in the offseason, they will have big questions about their defense and quarterback.

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AFC South Pick - My Pick

Indianapolis Colts (+1600) at Caesars Sportsbook

Taking the Texans at their current price is a bad bet, making the Colts the better play. While they don’t have Houston's talent, the team could get a spark with Anthony Richardson back at quarterback. Considering the Colts’ defense has been better, an offensive boost would be enough to overtake a shaky Texans squad. 

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Previous AFC South Winners

How to Read Future NFL Odds

NFL futures odds work the same as any other bet. Each bet includes a number following the team or player, preceded by a plus or minus sign. 

A plus sign before the number usually indicates an underdog, which is common with futures bets. If the odds next to a team or player have a plus sign, that is the amount that you will win for every $100 you bet.

A minus sign usually indicates the favorite to win, though they are rarely seen for future bets. A minus sign in front of the odds means that is how much you need to bet to win $100.

For example, you bet $100 on the Texans +100 to win the AFC South. If they win the division, you will win $100 

How to Choose the Best Sportsbook for Betting on the AFC South

Are you ready to start betting on the AFC South but unsure where to start? If so, we have you covered with our sportsbook reviews. Below is a comparison between some of the industry’s best NFL betting sites.

*Bonus Bets Expire in 7 Days. One New Customer Offer Only. Add’l terms.