AFC South Odds, Predictions, Best Picks 2025: Texans Capture Division Title

• The Texans clinched the division with a Week 15 win

• The Colts still have a chance to capture an AFC Wild Card spot

• Brian Thomas Jr. leads the Jags with 73 catches for 1,088 yards and nine TDs

The Houston Texans have clinched the top spot in the AFC South. It was an ugly race between teams with many flaws, but it still provided plenty of excitement. Below, we will share a recap of the season for each team and gauge how their future looks. 

Take a look at our podcast, Ride the Line, and explore Grant and Tanner's predictions for AFC South. Also, check out our rankings of the best football betting sites.

AFC South Odds

Odds from Caesars Sportsbook. Click the odds in the table below and claim: Bet $1, Double Your Winnings Your Next 10 Bets.

AFC South Predictions and Favorites to Win

Houston Texans (OFF) at Caesars Sportsbook

The Texans managed to clinch the division title with a Week 15 win against the Dolphins. However, the team struggled against the Chiefs the following week. That has been a theme for this talented team this season, leading to a far closer division race than many expected.

Houston came into the season with a lot of hype to make Super Bowl LIX, but that is no longer the case. An erratic season that has seen the offense struggle has led to some bad losses and shows that this team is not the powerhouse we thought it would be.

Houston’s defense has been elite, but the offense will need consistency if the Texans are to advance to the playoffs.

Indianapolis Colts (OFF) at Caesars Sportsbook

The Colts lost the division race in Week 15 after being annihilated by the Broncos. The team bounced back to beat the Titans last week to keep their postseason hopes alive, but they’ll need help to get there. Fortunately, Indy will close the season against two of the league’s worst teams: the Giants and Jaguars. 

The biggest question for this team is what to do with Anthony Richardson. The young quarterback continues to show flashes of greatness but is mistake-prone. While he is still early in his career, the team must decide whether to continue developing him or look for another option in the offseason.

Tennessee Titans (OFF) at Caesars Sportsbook

The Titans have lost four consecutive games and remain firmly planted at the bottom of the standings. As ugly as their 3-12 record is, the Titans have been competitive in many losses this season. That could set them up well if the team ends up with a top draft pick, and hopefully, they can address the sorry state of their quarterback room.

The Titans ' matchup with the Jaguars in Week 17 will present an interesting challenge. The two teams have the same record, meaning the loser will likely receive the higher draft pick. While we are often told that teams don’t want to lose intentionally, it sure looked like that was the case in the 10-6 game these teams played three weeks ago.

Jacksonville Jaguars (OFF) at Caesars Sportsbook

The Jags continue to be one of the worst teams in football. They have lost to the Jets and Raiders over the last two weeks, firmly establishing them as the AFC’s worst team. While Jacksonville finishes the season with two winnable games against the Titans and Colts, don’t expect them to be motivated to give up their current draft position.

This team will need to figure a lot out during the offseason, but it appears they have found a star in rookie receiver Brian Thomas Jr. He leads the team with 73 catches for 1,088 yards and nine touchdowns. Poor quarterback play hasn’t slowed the playmaker down, giving this team a solid base to build around.

Previous AFC South Winners

How to Read Future NFL Odds

NFL futures odds work the same as any other bet. Each bet includes a number following the team or player, preceded by a plus or minus sign. 

A plus sign before the number usually indicates an underdog, which is common with futures bets. If the odds next to a team or player have a plus sign, that is the amount that you will win for every $100 you bet.

A minus sign usually indicates the favorite to win, though they are rarely seen for future bets. A minus sign in front of the odds means that is how much you need to bet to win $100.

For example, you bet $100 on the Texans +100 to win the AFC South. If they win the division, you will win $100 

How to Choose the Best Sportsbook for Betting on the AFC South

Are you ready to start betting on the AFC South but unsure where to start? If so, we have you covered with our sportsbook reviews. Below is a comparison between some of the industry’s best NFL betting sites.

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