Colorado vs. Iowa Betting Prediction, Best Bets, and Odds

• Iowa defeated Colorado in the Sweet 16 of last season's Tournament, 87-77. Caitlin Clark scored 31 points and shot 50% from the floor (11-22).

• Iowa is 0-2 ATS in Tournament play; the OVER is 0-2.

• Colorado is 2-0 ATS in Tournament play and 15-18 ATS this season.

Caitlin Clark has been the story in women's college basketball all season, a story that Colorado would like to bring to an end in their Sweet 16 rematch with Iowa on Saturday at 3:30 p.m. ET at MVP Arena in Albany, New York, on ABC. 

Clark and the Hawkeyes are favored, but after seeing West Virginia pose a real threat to Iowa, bettors may not want to overlook the Buffaloes.

Sports Betting Promos for Colorado vs. Iowa

Having a bet on an exciting game such as Colorado vs. Iowa is a surefire way to turn a great game into an epic viewing experience. What could make it even better? After signing up for a new account with one of these sportsbooks, place your bet and utilize their March Madness welcome offer!

Colorado vs. Iowa Prediction and Odds 

Here is the betting line for Colorado vs. Iowa with odds from FanDuel:

• Point Spread: Colorado +7.5 (-110) | Iowa -7.5 (-110)

• Moneyline: Colorado +285 | Iowa -375

• Total: O/U 160.5 (-110/-110) 

Colorado Buffaloes (24-9)

The Buffs are a solid offensive team (No. 29 in scoring; 75.4 ppg) and may not have much trouble scoring against Iowa's shoddy defense (No. 306 in scoring defense; 71.2 ppg allowed). However, scoring points will not be the key to getting past the Hawkeyes and making the Elite Eight.

They have to slow down Caitlin Clark.

Of course, doing so is easier said than done. Colorado is a decent defensive team, but the Buffs have struggled against solid three-point shooting teams this season (No. 311 three-point percentage defense). Iowa is one of the best three-point shooting teams in the country.

Colorado will undoubtedly try taking a page from West Virginia's playbook. The Mountaineers held Iowa, the nation's No. 1 offense, to just 64 points, well off their season average of 92. But they'll need to find a way to play a physical style without getting into foul trouble.

West Virginia only gave up one basket in the fourth quarter, but that's all Iowa needed since they were 14 of 17 from the free-throw line.

Iowa Hawkeyes (31-4)

The Iowa Hawkeyes' recipe for success appears to be simple: Just give Caitlin Clark the ball. After all, she leads the team in just about every significant statistical category (scoring, rebounds, assists, steals, etc.). 

But, while she is an incredible player, even the best needs a little help from time to time.

Iowa must be prepared for Colorado to attempt to put a metaphorical blanket over Clark, leaving Hannah Stuelke and Kate Martin to pick up the slack. Stuelke, who ranks No. 5 in the country in field goal percentage (63.5%), proved she could carry the load when she put up 47 in a win over Penn State.

Martin is averaging 12.8 ppg and 6.8 rpg. Like Stuelke, she is a solid shooter from the floor, hitting 51.6% of her shots this season. 

Colorado vs. Iowa Pick

• PICK: OVER 160.5 (-110) at FanDuel Sportsbook

We expect Iowa to win this one, but an upset is possible if the Hawkeyes lay another egg like they did against West Virginia. While bettors should not count on that happening, it is hard to say whether Iowa will be able to cover a 7.5-point spread, and there is no value in betting the moneyline.

However, Iowa will not have another bad night from behind the arc as they did against West Virginia. Colorado is not good at defending against the three, and the Hawkeyes will take advantage of that. 

Iowa is accustomed to outscoring opponents and will be okay with Colorado's sharpshooters having a good day in what will be a high-scoring game.

How to Watch Colorado vs. Iowa

• Location: MVP Arena in Albany, New York

• Game Time & Date: 3:30 p.m. ET on Saturday, 3/30/2024

• TV Network: ABC

• Streaming: ESPN+ and streaming services like YouTube TV, Sling TV, and Hulu + Live TV.