Nuggets vs. Lakers Prediction and Odds: Denver Leads the Season Series 2-1

The NBA’s Wednesday night schedule is headlined by a Western Conference matchup between Nikola Jokic’s Denver Nuggets and Luka Doncic’s Los Angeles Lakers! For new users at FanDuel Sportsbook, you can bet $5 and receive $200 in Bonus Bets if your bet wins!

For the best NBA game previews, WSN has you covered with betting picks and tips every day throughout the 2024-25 NBA season! New sports bettors supporting their hometown Denver Nuggets can take advantage of the top Colorado sportsbook promos and bonuses before their matchup against the Los Angeles Lakers tips off!

It’ll be their fourth and final meeting of the regular season when the Nuggets and Lakers play on Wednesday night. The Nuggets enter this game off a win without their key players, while the Lakers have bounced back from a four-game losing streak to win back-to-back games. The match tips off at 10:00 PM EST at crypto.com Arena in Los Angeles, California.

Let’s check out the bets for the Nuggets vs. Lakers game and look at our NBA Player Props and Best Bets article for Wednesday, March 19.

Denver Nuggets vs. Los Angeles Lakers Betting Odds

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Denver Nuggets vs. Los Angeles Lakers Betting Pick

• My Pick: Denver Nuggets +1.5 (-106) at FanDuel Sportsbook

The Denver Nuggets and Los Angeles Lakers have gone back and forth all season. This will be the final match of the regular season campaign between these teams, and both are managing significant injuries. While LeBron James remains out, the Nuggets expect to have Jokic and Murray return to the lineup. It’ll be an offense-forward affair, but expect the Nuggets to find success once again behind their efficiency and the form of role players who’ve stepped up over their recent run.

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Denver Nuggets Preview

The Denver Nuggets are still in the hunt for the second seed in the NBA, but they’ve been cautious with their star players as the season approaches. They face the Lakers on Wednesday night for the fourth and final time, aiming to win the season series and climb back up the West standings.

The Nuggets are 3-2 over their last five games, losing to the Timberwolves and Wizards. They’re averaging 120.6 points per game on 49.9% from the field and 38.6% from three, but they're allowing 119.8 points on 47.7% shooting and 38.0% from deep. When they take the court on Wednesday night, the Nuggets aim to have Murray and Jokic back in the lineup.

Through 69 regular season games, the Denver Nuggets have posted a 33-35-1 ATS Record, ranking them 14th in the NBA. They have a 48.5% cover percentage, a +2.3 margin of victory, and a -0.3 ATS +/- this season.

The Denver Nuggets have been managing their players in this late phase of the season, allowing Aaron Gordon to step in for Nikola Jokic and Jamal Murray. This season, he’s averaging 13.8 points, 4.9 rebounds, and 1.5 threes per game on 52.1% from the field and 45.7% from three. He led the Nuggets in their last game, a win over the Warriors, putting up 38 points with four made threes as Jokic and Murray were held out of the contest.

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Los Angeles Lakers Preview

The Los Angeles Lakers have struggled in recent weeks, suffering from an injury to their leader, LeBron James. When they take on the Denver Nuggets on Wednesday night, Luka Doncic will try to level the season series and gain ground on their conference rivals in the West standings.

The Lakers have been inconsistent over their past five games without LeBron James. They have posted a 2-3 record, losing by a -0.2 point differential while allowing their opponents to shoot 45.2% from the field and 36.9% from three. They’ve tried to stay competitive by scoring 114.4 points per game, 45.2% from the field, and 39.6% from three.

Through 67 regular season games, the Los Angeles Lakers have posted a 38-28-1 ATS Record, ranking them sixth in the NBA. They have a 57.5% cover percentage, a +1.6 margin of victory, and a +1.2 ATS +/- this season.

While much of the focus on the Lakers revolves around LeBron James’ absence and Luka Doncic’s step into the limelight, Austin Reaves has stepped up to help lead the team. In 60 games for the Lakers this season, Reaves is averaging 19.6 points, 6.0 assists, 4.5 rebounds, and 2.6 threes per game on 44.6% from the field and 36.6% from three. In his last game, a win over the Spurs, Reaves put up 30 points, seven rebounds, six assists, and five made threes on 57.1% shooting.

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Denver Nuggets vs. Los Angeles Lakers Injury Report

• Denver Nuggets - (G) Christian Braun - Game Time Decision (Foot) - Braun did not play in Denver’s March 17 game against the Warriors.

• Denver Nuggets - (C) Nikola Jokic - Game Time Decision (Elbow) - Jokic did not play in Denver’s March 17 game against the Warriors.

• Denver Nuggets - (G) Jamal Murray - Game Time Decision (Ankle) - Murray did not play in Denver’s March 17 game against the Warriors.

• Denver Nuggets - (G) Julian Strawther - Out (Knee) - Strawther sustained a left knee sprain on March 2 and will be re-evaluated after four weeks.

• Denver Nuggets - (C) DaRon Holmes - Out for Season (Achilles) - Holmes returned to practice but isn’t expected to return until next season.

• Los Angeles Lakers - (F) Rui Hachimura - Game Time Decision (Knee) - Hachimura did not play in Los Angeles’ March 17 game.

• Los Angeles Lakers - (C) Trey Jamison - Game Time Decision (Illness) - Jamison did not play in Los Angeles’ March 17 game.

• Los Angeles Lakers - (F) LeBron James - Out (Groin) - James is expected to miss one more week as he recovers from a groin injury.

• Los Angeles Lakers - (C) Maxi Kleber - Out (Foot) - After undergoing right foot surgery in February, Kleber is expected to miss eight weeks.

How to Watch Denver Nuggets vs. Los Angeles Lakers

• Teams: Denver Nuggets vs. Los Angeles Lakers

• Location: crypto.com Arena, Los Angeles, CA

• Date: 10:00 PM, Wednesday, March 19, 2025

• TV:  ESPN