NBA Eastern Conference Winner Predictions, Odds & Best Bets 2025: Celtics Are the Heavy Favorite

• The Boston Celtics are the favorite to win the East in 2025!

• The top contender to win the East is the New York Knicks.

• Last year's Eastern Conference Champions were the Boston Celtics.

All holds at the top of the Eastern Conference, with the usual suspects taking the top contender slots. At WSN, we're locked in on the race for the 2025 NBA Eastern Conference Winner, offering the latest odds, predictions, and analyses for the 2024-25 NBA season!

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The Boston Celtics have reaffirmed their place as the favorite to win the Eastern Conference. Their division rivals, the New York Knicks, are hot on their tails, though, while the Cleveland Cavaliers won't be overlooked at the top of the Eastern Conference standings. Meanwhile, the Milwaukee Bucks have regained some form while the Orlando Magic try to remain competitive with their star men unavailable.

Let's check out the bets!

2025 NBA Eastern Conference Odds

Odds courtesy of FanDuel Sportsbook, as of December 17. Click on the odds in the table below to head to FanDuel Sportsbook and place your bets: Bet $5, Get $150 in Bonus Bets if Your Bet Wins. Check out our list of the best NBA betting sites for more betting opportunities.

NBA Eastern Conference Winner - My Pick

• My Pick: Boston Celtics to Win Eastern Conference (+110) at FanDuel

The Boston Celtics may not be in the lead for the Eastern Conference right now, but their quality is undeniable. A veteran-led outfit that has improved production from its role players, the Celtics are a team built for competing in the postseason. While Jayson Tatum and Jaylen Brown lead the way for the Celtics, their supporting cast and head coach have been central to their early title defense.

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Who Is the Favorite to Win the Eastern Conference in 2025?

Boston Celtics (-110) at FanDuel

• Head Coach: Joe Mazzulla

• Key Players: Jayson Tatum, Jaylen Brown, Jrue Holiday

• Key Additions: Baylor Schelerman

• Key Losses: Oshae Brissett

The Boston Celtics have maintained their place in the Eastern Conference for much of the season thanks to a strong start and consistent play. Since the beginning of December, they’ve posted a 5-1 record, including important victories over Eastern Conference contenders. Their offense has been a key factor, highlighted by a steady three-point attack led by Jayson Tatum. Over their last six games, the team has averaged 18.8 made three-pointers per game while shooting 35.9% from beyond the arc. While their bench plays a big factor in their success, Joe Mazzulla has found that empowering their play rather than seeking raw production has allowed all parties to thrive.

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Who Are the Contenders to Win the NBA Eastern Conference in 2025?

New York Knicks (+500) at FanDuel

• Head Coach: Tom Thibodeau

• Key Players: Jalen Brunson, Karl-Anthony Towns, Mikal Bridges

• Key Additions: Karl-Anthony Towns, Mikal Bridges, Cameron Payne

• Key Losses: Julius Randle, Donte DiVincenzo, Isaiah Hartenstein

The New York Knicks have started to build some momentum in December, winning four of their last six games and narrowing the gap between them and the Celtics in the Eastern Conference standings. Benefiting from a manageable schedule, they picked up solid wins against the Magic, Hornets, and Raptors. Although defensive consistency remains an area of concern, the offense, led by Jalen Brunson and Karl-Anthony Towns, has been productive. Over this six-game stretch, the Knicks have averaged 111.7 points per game while shooting 49.6% from the field and 39.4% from beyond the arc. With four games in six days coming up, the Knicks will see one of their toughest tests of the season.

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Cleveland Cavaliers (+600) at FanDuel

• Head Coach: Kenny Atkinson

• Key Players: Donovan Mitchell, Evan Mobley, Jarrett Allen

• Key Additions: JT Thor, Luke Travers, Jaylon Tyson

• Key Losses: Marcus Morris, Isaiah Mobley, Damian Jones

Still at the top of the Eastern Conference, the Cleveland Cavaliers remain the standard through the early regular season. They have gone 4-1 over the past two weeks, holding their opponents to 106.0 points per game on 45.1% from the field and 30.7% from three-point range. They’ve had a relatively beneficial schedule, but an impressive win over the Denver Nuggets highlighted their week. While Cleveland has been balanced in their production this season, Donovan Mitchell can improve on a period where he put up 19.4 points, 6.4 assists, and 4.6 rebounds per game.

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Milwaukee Bucks (+1100) at FanDuel

• Head Coach: Doc Rivers

• Key Players: Giannis Antetokounmpo, Damian Lillard, Khris Middleton

• Key Additions: Gary Trent Jr., Delon Wright, Taurean Prince

• Key Losses: Malik Beasley, Patrick Beverley, Jae Crowder

The Milwaukee Bucks have picked up the pace after a disappointing start to the season. Back over the .500 mark with a positive run to the Emirates NBA Cup Final, the Bucks have reclaimed a season many thought was lost. Going 4-2 over the last two weeks, the Bucks faltered against the Hawks and Celtics in regular season play before heading to the Emirates NBA Cup knockout phase. If they hope to compete for the East, the Bucks must earn statement victories over their rivals in the conference.

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Who Is the Dark Horse to Win the 2025 NBA Eastern Conference?

Orlando Magic (+1500) at FanDuel

• Head Coach: Jamahl Mosley

• Key Players: Paolo Banchero, Franz Wagner, Jalen Suggs

• Key Additions: Kentavious Caldwell-Pope, Tristan Da Silva, Cory Joseph

• Key Losses: Markelle Fultz, Joe Ingles

The Orlando Magic have had an eventful start to the regular season. While they’ve been one of the best teams in the Eastern Conference, they’ve also been ravaged by injury as the schedule has worn on. The Magic are 2-4 over the past two weeks, with wins over the Suns and Sixers, while they’ve dropped games to the Knicks and Bucks. With Banchero and Wagner out of the lineup, the Magic can’t be looked at as the final product, but it’ll be an interesting test to see how Jamahl Mosley and his squad manage without their star men available.

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