Best MLB Prop Bets Today: MLB Player Props, April 5
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Best MLB Prop Bets for Today: What Pitchers Are Set Up for Success on Saturday?

Published: Apr. 5, 2025, 12:13 PM ET
5 min read
Best MLB Bets Today 2024 07 30 Blue Jays Chris Bassitt

Making prop bets doesn’t have to stop just because it’s the weekend. For Saturday, we have a lineup of prop bets made entirely of pitchers, most of whom we expect to succeed. After all, in early April, pitchers should have the advantage, so we’re going to run with that.


The odds for Saturday’s best are from bet365 Sportsbook, which is a great platform for both experienced and novice prop bettors. It might be a little better for beginners because new bet365 customers have a choice between a safety net of up to $1,000 on their first bet or $150 in bonus bets.

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Best MLB Prop Bets Today: Rays vs Rangers (7:05 PM, EST)

Jacob deGrom Under 3.5 Hits (-120) at bet365 Sportsbook

Guess who looked healthy and dominant in his first start of the season? Injuries have plagued the two-time Cy Young winner for years, but when deGrom is healthy, he’s an exceptional pitcher. He tossed five scoreless innings against the Red Sox in his first start of the season, so while he’s still healthy, we’re going to target him for another strong showing against the Rays. Most members of Tampa’s lineup have never faced deGrom before, which will make it even more difficult to face the Texas ace. Plus, the Rays have only mustered 10 total hits over their past two games, which should make it difficult to scratch out more than three hits against deGrom, especially if the Rangers don’t try to push him beyond five or six innings early in the year.

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Best MLB Prop Bets Today: Blue Jays vs Mets (7:10 PM, EST)

Chris Bassitt Under 5.5 Strikeouts (-120) at bet365 Sportsbook

Bassitt struck out seven batters in his first start of the season. But that may have raised expectations for his strikeout total in his second start. Bassitt went over five strikeouts just once in his five April starts last season. He also has a tough matchup against the Mets, who have the second-fewest strikeouts in the big leagues this season. Toronto pitchers combined for just one strikeout in Friday’s game against the Mets, who look like they’re starting to click offensively. They’re going to keep putting together quality at-bats, making it tough for Bassitt to rack up a high strikeout total.

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Best MLB Prop Bets Today: Athletics vs Rockies (8:10 PM, EST)

German Marquez Under 1.5 Walks (-125) at bet365 Sportsbook

The Rockies have the best rotation in baseball through the early part of the season, with Marquez being a big reason why. He dominated the Phillies over six scoreless innings in his first start of the season, giving up just four hits and no walks. There’s no reason to think that Marquez won’t be able to keep it going against the A’s on Saturday. While he’s barely pitched the last two seasons, Marquez has always had solid control and a low WHIP. Plus, only three teams are averaging fewer walks per game than the Athletics thus far, which should help Marquez avoid any free passes.

JP Sears Over 5.5 Strikeouts (+105) at bet365 Sportsbook

Despite Colorado’s excellent pitching, the Rockies have been an abomination offensively. They’ve been held to two runs or less in five of their seven games while averaging 11.7 strikeouts per game, which is the most in the majors. That makes it a no-brainer to target Sears’s strikeout total on Saturday. While he took the loss in his first start, Sears looked good, striking out seven over 6.2 innings against the Mariners. Even if he’s not always a high-strikeout pitcher, Sears proved in his last outing that he can miss bats. He should have no problem doing the same against a struggling Colorado lineup.

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Best MLB Prop Bets Today: Mariners vs Giants (9:05 PM, EST)

Bryce Miller Over 4.5 Strikeouts (-150) at bet365 Sportsbook

The Giants are another team that’s had trouble avoiding punch-outs this season, averaging more than 10 per game, which is why we’re targeting Miller. While not known as a high-strikeout pitcher, Miller has averaged close to a strikeout per inning during his first two seasons in the big leagues. If he can pitch five or six innings against the Giants, he should be able to top 4.5 strikeouts, which is a modest total for a quality starting pitcher. Miller could also have an edge because most members of the Giants have never faced him before. That should allow Miller to rack up some strikeouts early and get over 4.5 punch-outs.

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Bryan Zarpentine WSN Contributor

Bryan Zarpentine

Sports Betting Analyst

Expertise:
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NCAAB
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Bryan Zarpentine is a 2008 graduate of Syracuse University and has been working as a freelance writer and editor since 2010. During that time, he has contributed to countless sites while covering baseball, soccer, the NFL, college football, and college basketball.
Email: [email protected]
Nationality: American
Education: Bachelor of Arts
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Experience: 14 years
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