Best MLB Parlay Picks Today: Target the Pirates With Paul Skenes on the Bump

Paul Skenes takes the mound for the Pirates against Kyle Hendricks and the Cubs on Wednesday. We are backing the Pirates in this matchup on the moneyline at -168.

We are also taking the under in the Royals vs. Guardians game, and the Yankees on the moneyline. We’re placing this parlay on bet365 Sportsbook. 

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Let’s dive into our three-leg parlay that you can get at +380.

MLB Parlay Picks Today: Cubs vs. Pirates (12:35 PM, EST)

Pirates Moneyline (-168) at bet365

A pair of NL Central teams square off in Pittsburgh on Wednesday afternoon. The Cubs come into this matchup at 66-66 in second place in this division. The Pirates are 62-69 trailing Chicago by 3.5 games. 

Kyle Hendricks takes the mound for Chicago who has not had the best season in 2024. He is 3-10 with an ERA of 6.33. Hendricks has struck out 67 batters in 101 innings and has a 1.45 WHIP. 

He will go up against Paul Skenes who is 8-2 with a 2.16 ERA. Skenes has been impressive in 2024 as he has a WHIP of 0.94 and has struck out 130 batters in 104 innings. Look for Skenes to rack up the strikeouts in this favorable matchup against the Cubs. 

We expect Skenes to deliver a quality start and for Pittsburgh to score many runs off a struggling Hendricks.

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MLB Parlay Picks Today: Royals vs. Guardians (1:10 PM, EST)

Under 8 (-105) at bet365

One of the most important games on Wednesday includes a matchup between two AL Central squads. Kansas City is 74-58 in second place in this division. Cleveland is 75-57, leading the Royals by one game in the division. 

Michael Wacha takes the mound for the Royals who is 11-6 in 2024. He has an ERA of 3.32 and has only allowed four runs in his last 19 innings. Wacha has been a veteran presence on this team, and we expect him to dominate again on Wednesday. 

The Guardians are going with Tanner Bibee who is 10-6 with a 3.46 ERA. He has fanned 150 batters in 138 innings and has a 1.10 WHIP. Bibee is familiar with the Royals lineup being an AL Central opponent, and we expect him to strive in this environment. 

Look for very few runs to be scored in this game as we are trusting both pitchers to take care of business. 

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MLB Parlay Picks Today: Yankees vs. Nationals (6:45 PM, EST)

Yankees Moneyline (-184) at bet365

To close out our parlay, we are taking the Yankees moneyline against the Nationals. New York is 78-54 with a two game lead on Baltimore in the AL East. Washington comes into this matchup at 59-73 in fourth place in the NL East. 

Carlos Rodon will make the start for the Yankees who is 14-8 with a 4.16 ERA in 2024. He has 153 strikeouts in 140.2 innings and has a great advantage in this matchup against Washington. 

The Nationals are going with Mackenzie Gore who is 7-11 with an ERA of 4.51. He has fanned 140 batters in 131.2 innings and has a 1.56 WHIP. Gore is coming off a great start against Atlanta, and we do not expect him to repeat that in this game. 

We expect Rodon to get ahead of hitters and shut down Washington’s bats. Look for Aaron Judge and Juan Soto to dominate in this matchup to cash our parlay.

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