Puebla vs. Mazatlan Prediction: Hosts Seek First Win in the Clausura

Tuesday evening Puebla will host Mazatlan down at Estadio Cuauhtemoc in a midweek clash in round four of the 2025 Clausura campaign. The most recent encounter occurred in the previous term that saw both clubs share the points in August in a 1-1 draw. Head-to-head the preceding 10 skirmishes, Los Camoteros posses the edge winning in six instances versus Mazatlan’s two, while both teams shared a result two times. 

Pablo Guede’s first year as the dugout boss for Puebla is off to a subpar start, as they have collected two points through three matches, currently sitting 15th overall in Liga MX. Over the weekend Los Camoteros secured a valuable road point against Cruz Azul, drawing 1-1. 

Meanwhile, Víctor Manuel Vucetich's men recorded their first win in 2025, defeating Toluca 2-1 last weekend. Currently, the Canoneros are placed in ninth spot overall in the Clausura table posting four points in their first three games played. 

Here, we will break down the betting odds and share our favourite picks for Puebla vs. Mazatlan.

Puebla vs. Mazatlan Betting Odds for Tuesday, January 28

Rolling into this midweek fixture, the books have favoured that this contest will feature both teams finding the scoresheet. For both teams to score, the price is listed at -143. Both clubs failed to score on Tuesday, the books have listed the number at +105.

Puebla vs. Mazatlan Odds

Puebla vs. Mazatlan Betting Prediction

Our preferred sportsbook for this Liga MX matchup is bet365. Use our promo code WSN365 at bet365 to claim $150 in Bonus Bets.

Puebla Preview

Scoring the lone goal in Puebla’s tie last weekend, Emiliano Gomez found the back of the net, scoring his first tally in the 2025 Clausura season. The 23-year-old striker bagged three goals in his first taste of Liga MX last year, appearing in 13 matches throughout the 2024 Apertura.

Arguably the most lethal striker on this roster, is still out with an injury as Lucas Cavallini's estimated return date is in March. The Canadian international has repped a Puebla kit in 103 outings across all competitions played, amassing 37 goals during his three different stints with the team.

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Mazatlan Preview

Luis Amarilla's strike in the 76th minute against Toluca ended up as the game-winner for Mazatlan on Friday night. The striker played till the final whistle, logging an assist, giving him three goal contributions in as many games to open up the new season. The 29-year-old has cataloged 12 goals in all competitive matches played since joining the Canoneros in June 2023.

Registering the game's first marker last week was center-back Facundo Almada in the 17th minute. The 26-year-old played the full 90-minute shift in doing so he finished as the most accurate passer in the match with an 89 percent success rate going 33-for-37.

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Puebla vs. Mazatlan - My Pick

• Puebla vs. Mazatlan pick: Both teams to score YES (-143) at bet365

Approaching Tuesday's battle, both clubs have performed nicely on the scoreboard, helping ensure our wager can cash. Between both opponents, every match they have featured in through three rounds has resulted in both teams hitting the back of the mesh. We feel this trend should occur once again especially with this matchup taking place at Estadio Cuauhtemoc. Covering all conflicts to take place, both teams have been able to breach each keeper in four of the five matches all time. With the recent trends in the 2025 Clausura and historical meetings, we feel this is a good opportunity for both teams to score.

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How to Watch Puebla vs. Mazatlan

• When: January 28, 8 p.m. ET

• Where: Estadio Cuauhtemoc

• TV: FOX Deportes, Univision, UniMas, Telemundo, Universo, TUDN, ESPN Deportes, ESPN+ and ViX+